Cytotec

Common Name: misoprostol

How does Cytotec work?

Misoprostol belongs to the class of medications called synthetic prostaglandins. This medication is used to treat and prevent stomach (gastric) and intestinal (duodenal) ulcers. It is used to treat and prevent ulcers caused by a class of painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs). It is also used to treat ulcers caused by peptic ulcer disease, which are most often caused by H. pylori (a bacteria that causes ulcers of the stomach and intestine). Misoprostol is a synthetic prostaglandin which acts just like the natural prostaglandin that is found in your body. It works by decreasing acid and increasing mucus and blood flow to the stomach, which protects the walls of the stomach and intestine. Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

How should I use Cytotec?

The recommended adult dose of misoprostol ranges from 400 µg to 800 µg daily taken in two to four equally divided doses (e.g., 100 µg four times daily, 200 µg twice daily, 200 µg four times daily). Misoprostol should be taken with food or milk to reduce risk of side effects such as diarrhea. Also, to reduce the risk of diarrhea, avoid antacids containing magnesium. Antacids containing aluminum (but not magnesium) may be used to relieve symptoms such as heartburn. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. It is important that this medication be taken exactly as prescribed by the doctor. This medication may cause loose stools, diarrhea, and abdominal cramping while your body adjusts to it. These symptoms should go away within a few days. Do not stop the medication without first talking with your doctor. If you miss a dose, take it as soon as possible and continue on with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. Do not double doses.

What form(s) does Cytotec come in?

Cytotec® is available in strengths of 100 µg and 200 µg. 100 µg: Each white-to-off-white, round tablet, with "SEARLE" engraved on one side and "CYTOTEC" on the other, contains misoprostol 100 µg. 200 µg: Each white-to-off-white, scored, hexagonal tablet, with "SEARLE 1461" engraved on one side, contains misoprostol 200 µg. Nonmedicinal ingredients: cellulose, hydrogenated castor oil, hydroxypropyl methylcellulose, and sodium starch glycolate.

What should I NOT take with Cytotec?

Misoprostol should not be used by: pregnant women anyone allergic to misoprostol or to any of the ingredients of the medication

Are there any other precautions or warnings for Cytotec?

Diarrhea: Rare instances of severe diarrhea leading to dehydration have been reported with use of this medication. People with an underlying condition such as irritable bowel disease or those for whom dehydration would be dangerous should be monitored closely by their doctor. Epilepsy: Epileptic seizures have been reported with medications like misoprostol when administered by routes other than oral (by mouth). Therefore, misoprostol should be used by people with epilepsy only when their epilepsy is adequately controlled and the expected benefits outweigh the potential risks. Pregnancy: Women who may become pregnant should use adequate birth control (e.g., birth control pills, condoms, or intrauterine devices) while taking misoprostol. Since misoprostol increases the risk of miscarriage, a woman who may be pregnant should not start taking misoprostol until she is sure that she is not. If you suspect you are pregnant, stop the medication and contact your doctor. Breast-feeding: Breast-feeding mothers should not take misoprostol, as it may cause significant diarrhea for nursing infants. Children: The safety and effectiveness of this medication have not been established for those younger than 18 years of age.